BridgeMD
Phase IV study comparing three methods to trigger ovulation in IVF treatment with fresh embryo transfer.
EU CTIS ID: 2026-526292-37-01
What this study is testing
To evaluate whether the addition of follitropin δ to hCG ovulation triggering increases the number of mature (MII) oocytes in women with low ovarian reserve undergoing fresh embryo transfer IVF cycles.
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Signed informed consent.
- Women aged 18 to 42 years old.
- Primary infertility.
- Women with poor ovarian response who meet any of the groups defined by the POSEIDON criteria.
You likely can't join if
- More than two failed ovarian stimulation cycles.
- Severe male factor (total motile sperm count [TMSC] <1 million).
- Female age >42 years.
- BMI >35.
- Criteria for extremely low ovarian reserve meeting Spanish National Health System (SNS) exclusion criteria (AMH <0.3 ng/mL and/or AFC <5).
- Previous healthy child shared by the couple.
See the full eligibility criteria
- Signed informed consent.
- Women aged 18 to 42 years old.
- Primary infertility.
- Women with poor ovarian response who meet any of the groups defined by the POSEIDON criteria.
- More than two failed ovarian stimulation cycles.
- Severe male factor (total motile sperm count [TMSC] <1 million).
- Female age >42 years.
- BMI >35.
- Criteria for extremely low ovarian reserve meeting Spanish National Health System (SNS) exclusion criteria (AMH <0.3 ng/mL and/or AFC <5).
- Previous healthy child shared by the couple.
- Presence of medical conditions contraindicating pregnancy.
- Risk of ovarian hyperstimulation syndrome (OHSS). If more than 15 follicles are anticipated on the day of oocyte retrieval, the patient will be excluded from the study.
- Previous voluntary sterilization (bilateral tubal ligation in the woman / vasectomy in the male partner).
- Male partner age >55 years.
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.