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Enhancing infant mucosal immunity through vaccination during lactation.
EU CTIS ID: 2025-524862-12-00
What this study is testing
The main objective of this study is to investigate the humoral immune response to MMR vaccination in breastmilk over a 3-month period. This will allow us to determine to which extent a booster MMR dose during lactation can induce more antibodies against measles, as compared to unvaccinated lactating women, and to study the waning of this response over time.
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Age between 18 and 45 years, healthy
- Intention to breastfeed for more than 2 months
- Capable of giving consent for themselves
You likely can't join if
- Inability to understand the nature and extent of the study and the procedures required
- Blood hemorrhage >500 mL during delivery
- Acute infection at the time of delivery or in the last 7 days of pregnancy
- Grade III/IV anaemia
- Chronic infections such as HBV , HCV or HIV infection; acute toxoplasmosis
- Current or recent use of immunosuppressive drugs
See the full eligibility criteria
- Age between 18 and 45 years, healthy
- Intention to breastfeed for more than 2 months
- Capable of giving consent for themselves
- Inability to understand the nature and extent of the study and the procedures required
- Blood hemorrhage >500 mL during delivery
- Acute infection at the time of delivery or in the last 7 days of pregnancy
- Grade III/IV anaemia
- Chronic infections such as HBV , HCV or HIV infection; acute toxoplasmosis
- Current or recent use of immunosuppressive drugs
- Active neoplasia
- Twin or triplet pregnancies
- Infants born before 35 weeks of gestation
- Infant birthweight below 2.5 kg
- Infant serious congenital abnormalities or congenital infection
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 0-17 years, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.