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Doxycycline post-exposure prophylaxis: Weekly versus event-driven Intake for STI prevention among MSM and TGW taking PrEP
EU CTIS ID: 2025-524823-34-00
What this study is testing
Assess if Weekly-DoxyPEP is non-inferior to Event-Driven-DoxyPEP in terms of the incidence rate of Neisseria gonorrhoeae (NG)/ Chlamydia trachomatis (CT) and Treponema pallidum (TP) infections among MSM and TGW taking HIV-PrEP in Belgium
- Therapeutic confirmatory (Phase III)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Able and willing to provide informed consent in Dutch or English and adhere to the study procedures
- Aged 18 years or older
- Assigned male sex at birth
- Identifying as gay, bisexual or other men who have sex with men or transgender women
- Enrolled in PrEP care
- Being HIV negative
You likely can't join if
- Hypersensitivity to doxycycline or any substance used in the IMP
- Concomitant use of medication interacting with doxycycline
- Any contra-indication to the use of doxycycline, as mentioned in the summary of product characteristics
See the full eligibility criteria
- Able and willing to provide informed consent in Dutch or English and adhere to the study procedures
- Aged 18 years or older
- Assigned male sex at birth
- Identifying as gay, bisexual or other men who have sex with men or transgender women
- Enrolled in PrEP care
- Being HIV negative
- Reporting having had condomless anal sex with at least one non-steady partner in the preceding year
- Hypersensitivity to doxycycline or any substance used in the IMP
- Concomitant use of medication interacting with doxycycline
- Any contra-indication to the use of doxycycline, as mentioned in the summary of product characteristics
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 18-64 years, 65+ years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.