Authorised Therapeutic use (Phase IV) Diabetic foot ulcer

Healing Diabetic Foot Ulcers with Semaglutide

EU CTIS ID: 2025-524738-24-00

What this study is testing

To demonstrate the effect of semaglutide on the time to wound closure in patients with a diabetic foot wound.

  • Therapeutic use (Phase IV)

A plain-language read of the study's public EU CTIS listing. The study team confirms the details.

Who can take part

You may be able to join if

  • Have type 2 diabetes mellitus (T2DM)
  • Presence of an active diabetic foot ulcer
  • Age >18 years
  • Be proficient in either Dutch or English

You likely can't join if

  • Those with current use or who used a GLP-1RA or GLP-1/GIP co-agonist in the previous 6 months.
  • Any contra-indication for semaglutide as outlined in the EPAR (which only consists of allergy to the contents of semaglutide injections)
  • Current pregnancy
  • Previous pancreatitis attributed to use of GLP-1RA
  • End-stage renal disease (defined as estimated-GFR <15 mL/min/m2 or the use of renal replacement therapy)
  • Current use of anti-inflammatory therapy, e.g. prednisolone
See the full eligibility criteria
Who can join
  • Have type 2 diabetes mellitus (T2DM)
  • Presence of an active diabetic foot ulcer
  • Age >18 years
  • Be proficient in either Dutch or English
What rules you out
  • Those with current use or who used a GLP-1RA or GLP-1/GIP co-agonist in the previous 6 months.
  • Any contra-indication for semaglutide as outlined in the EPAR (which only consists of allergy to the contents of semaglutide injections)
  • Current pregnancy
  • Previous pancreatitis attributed to use of GLP-1RA
  • End-stage renal disease (defined as estimated-GFR <15 mL/min/m2 or the use of renal replacement therapy)
  • Current use of anti-inflammatory therapy, e.g. prednisolone
  • Life expectancy <3 months

The study team makes the final eligibility decision.

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.