BridgeMD
Rollover study for participants who are currently being treated with and are continuing to benefit from opnurasib as a single agent or in combination with other study treatments.
EU CTIS ID: 2025-523537-26-00
What this study is testing
The primary objective of this rollover study is to provide continued access to opnurasib, administered as monotherapy or in combination, for participants who continue to derive clinical benefit from parent protocols.
- Phase I and Phase II (Integrated)- Other
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Signed informed consent must be obtained prior to participation in the study.
- Participant is currently enrolled in a pre-defined Novartis-sponsored study and is receiving opnurasib as single agent or in combination with other study treatment.
- Participant has received at least 6 cycles of opnurasib in a parent study
- Participant is currently deriving clinical benefit from the study treatment, as determined by the Investigator
- Participant has demonstrated compliance, as assessed by the Investigator, with the parent protocol requirements.
- Participant is willing and able to comply with the scheduled visits and treatment plans.
You likely can't join if
- Participant has been permanently discontinued from opnurasib in the parent protocol for any reason other than enrollment in the CJDQ443B12105B study
- Participant is not willing to comply with the contraception requirements outlined in the exclusion criteria of the parent protocol
- Participant currently has unresolved toxicities for which opnurasib dosing has been interrupted in the parent study
The study team makes the final eligibility decision.
Where it's taking place
- Canada
- Malaysia
- Japan
- Singapore
- China
- Korea, Republic of
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Canada; Malaysia; Japan; Singapore; China; Korea, Republic of. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.