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Is magnesium sulfate an alternative with an analgesic and safety profile equivalent to dexmedetomidine as an adjuvant to ropivacaine in erector block in mastectomy?
EU CTIS ID: 2025-523152-31-00
What this study is testing
The main objective of this study is to determine whether magnesium sulfate as an adjuvant to 0.3% ropivacaine in erector spinae plane (ESP) blockade in mastectomy surgery offers an analgesic profile comparable to that of dexmedetomidine in terms of duration of postoperative analgesia based on the interval between recovery from general anesthesia and the time of the first request for rescue analgesia.
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- • Patients aged 18 to 75 years scheduled for elective mastectomy under general anesthesia
- • ASA I-III patients
- • No contraindications for locoregional anesthesia
You likely can't join if
- • Allergy to study drugs or local anesthetics.
- • Uncooperative patients.
- • Body mass index (BMI) > 35 kg/m².
- • Coagulopathy or bleeding disorder.
- • Pre-existing bradycardia or cardiac conduction block.
- • Psychiatric illness.
See the full eligibility criteria
- • Patients aged 18 to 75 years scheduled for elective mastectomy under general anesthesia
- • ASA I-III patients
- • No contraindications for locoregional anesthesia
- • Allergy to study drugs or local anesthetics.
- • Uncooperative patients.
- • Body mass index (BMI) > 35 kg/m².
- • Coagulopathy or bleeding disorder.
- • Pre-existing bradycardia or cardiac conduction block.
- • Psychiatric illness.
- • Pregnancy.
- • Injection site infection.
- • Patients receiving α-adrenergic agonists or antiplatelet agents.
- • Chronic opioid use.
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.