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A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer
EU CTIS ID: 2025-522204-24-00
What this study is testing
To compare the efficacy of LY3537021 in combination with other antiemetic treatments to placebo in combination with other antiemetic treatments
- Therapeutic exploratory (Phase II)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Need treatment with an anti-cancer regimen that includes cisplatin or anthracycline and cyclophosphamide.
- Be well enough to walk and do light work.
You likely can't join if
- Have had chemotherapy before.
- Need to receive chemotherapy from Day 2 to Day 5 of each cycle.
- Have cancer that has spread to the brain and/or spinal cord and is causing noticeable symptoms or has not yet been treated.
- Have uncontrolled diabetes or a serious heart problem or conditions related to the heart rhythm.
- Have another cause for nausea and vomiting, or receive medications known to prevent or treat nausea and vomiting.
- Have signs, symptoms, or history of thyroid tumors.
See the full eligibility criteria
- Need treatment with an anti-cancer regimen that includes cisplatin or anthracycline and cyclophosphamide.
- Be well enough to walk and do light work.
- Have had chemotherapy before.
- Need to receive chemotherapy from Day 2 to Day 5 of each cycle.
- Have cancer that has spread to the brain and/or spinal cord and is causing noticeable symptoms or has not yet been treated.
- Have uncontrolled diabetes or a serious heart problem or conditions related to the heart rhythm.
- Have another cause for nausea and vomiting, or receive medications known to prevent or treat nausea and vomiting.
- Have signs, symptoms, or history of thyroid tumors.
- Receive treatment with medications called incretins within 4 weeks before chemotherapy.
The study team makes the final eligibility decision.
Where it's taking place
- Taiwan
- Australia
- Japan
- Turkey
- United States
- China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Taiwan; Australia; Japan; Turkey; United States; China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.