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Pre- and post-treatment evaluation of lung function with Xenon-gas enhanced Dual-Energy CT-imaging in patients undergoing radiotherapy
EU CTIS ID: 2025-521559-22-00
What this study is testing
The primary objective of this trial is to acquire high-resolution anatomical and functional information on lung ventilation using a gas mixture of 30 Vol% Xe in 70 Vol% O2 as contrast agent in combination with DECT-imaging in lung and breast cancer patients scheduled to undergo radiotherapy. Ventilation maps will be generated to evaluate the effect of radiotherapy on the lung parenchyma in lung and breast cancer patients.
- Phase II and Phase III (Integrated)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Lung and breast cancer having a TNM classification I-IIIa.
- Between 50 and 80 years old.
- No prior cancer treatment.
- Breath hold for 3 seconds
- Patients who are in stable condition or who are not hospitalized in an ICU.
- Patients who are not suffering from COPD GOLD IV.
You likely can't join if
- No lung or breast cancer having a TNM classification I-IIIa.
- Younger than 50 or older than 80 years old.
- Received prior cancer treatment.
- Cannot perform a 3 s breath hold
- Patients who are in an unstable condition or who are hospitalized in ICU.
- Patients who are suffering from COPD GOLD IV.
See the full eligibility criteria
- Lung and breast cancer having a TNM classification I-IIIa.
- Between 50 and 80 years old.
- No prior cancer treatment.
- Breath hold for 3 seconds
- Patients who are in stable condition or who are not hospitalized in an ICU.
- Patients who are not suffering from COPD GOLD IV.
- Patients who signed informed consent forms.
- No lung or breast cancer having a TNM classification I-IIIa.
- Younger than 50 or older than 80 years old.
- Received prior cancer treatment.
- Cannot perform a 3 s breath hold
- Patients who are in an unstable condition or who are hospitalized in ICU.
- Patients who are suffering from COPD GOLD IV.
- Patients who did not sign informed consent forms.
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.