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Botulinum toxin injection after sternotomies to improve scar aspect and impact
EU CTIS ID: 2025-521290-14-00
What this study is testing
The main objective was to evaluate the improvement of scar appearance by botulinum toxin injection in the immediate postoperative period after sternotomy, according to the Stony Brook Scar Evaluation Scale.
- Therapeutic confirmatory (Phase III)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Patient aged 18 years old or over
- Surgery with sternotomy
- Covered by medical insurance
- Patient able to attend follow-up visits
- Patient able to sign informed consent
You likely can't join if
- Known allergy to botulinum toxin type A or to one of BOTOX®'s excipients (human albumin, sodium chloride)
- Subclinical or clinical manifestations of abnormal neuromuscular transmission (myasthenia or Lambert-Eaton syndrome)
- Peripheral motor neuropathy (such as amyotrophic lateral sclerosis or motor neuropathy)
- Treatment with drugs that interfere directly or indirectly with neuromuscular transmission (aminoglycosides, curares, anticholinesterase agents, aminoquinoline, cyclosporine, etc.)
- History of neuromuscular disorders
- Injection site infection
See the full eligibility criteria
- Patient aged 18 years old or over
- Surgery with sternotomy
- Covered by medical insurance
- Patient able to attend follow-up visits
- Patient able to sign informed consent
- Known allergy to botulinum toxin type A or to one of BOTOX®'s excipients (human albumin, sodium chloride)
- Subclinical or clinical manifestations of abnormal neuromuscular transmission (myasthenia or Lambert-Eaton syndrome)
- Peripheral motor neuropathy (such as amyotrophic lateral sclerosis or motor neuropathy)
- Treatment with drugs that interfere directly or indirectly with neuromuscular transmission (aminoglycosides, curares, anticholinesterase agents, aminoquinoline, cyclosporine, etc.)
- History of neuromuscular disorders
- Injection site infection
- Previous surgery with general anesthesia (curarization) in the month prior to inclusion
- Pregnancy or breastfeeding
- Persons under court protection, guardianship or conservatorship
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.