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Randomized clinical trial to assess the efficacy and safety of a strategy for primary prevention of cardiovascular disease in patients with inflammatory rheumatic diseases based on the use of carotid ultrasound.
EU CTIS ID: 2025-521086-28-00
What this study is testing
To analyze the efficacy of a primary prevention strategy for CV events in patients with inflammatory rheumatic diseases based on the use of carotid ultrasound to identify and treat those patients at high CV risk classified in the low-moderate SCORE groups, comparing it with the current strategy based on clinical guidelines.
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Patients who have given written informed consent.
- Patients ≥50 years of age
- Patients meeting classification criteria for any of the following rheumatic CIS: rheumatoid arthritis (RA, ACR/EULAR criteria) or psoriatic arthritis (PsA, CASPAR criteria) or axial spondyloarthritis (EspAax, ASAS criteria) or systemic lupus erythematosus (SLE, ACR/EULAR criteria) (annex IV)
- Patients included in the low-moderate CV risk groups according to SCORE2/OP (Annex V)
You likely can't join if
- Presence of CV events, type 2 DM, familial hypercholesterolemia or chronic kidney disease that imply classification in the high/very high CV risk groups.
- Patients who, either in the context of research studies or as a result of decisions made in routine clinical practice, and meeting the previously mentioned inclusion criteria, have undergone carotid ultrasound and therapeutic intervention as a consequence.
- Patients with contraindications to lipid-lowering therapies, including a history of recent alcoholism and the presence of active liver disease or with unwarranted and persistent elevations of serum transaminases exceeding three times the maximum normal value (for statins and ezetimibe).
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.