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A clinical study of tulisokibart to treat radiographic axial spondyloarthritis (MK-7240-013)
EU CTIS ID: 2025-521059-21-00
What this study is testing
To evaluate the efficacy of tulisokibart compared with placebo as assessed by the proportion of participants achieving ASAS 40 response at Week 16.
- Therapeutic exploratory (Phase II)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Has a clinical diagnosis of axial spondyloarthritis (axSpA) and meets the ASAS classification criteria for axSpA including ≥3 months of back pain with age at symptom onset <45 years.
You likely can't join if
- Has any arthritis with onset before age 17 years or current diagnosis of inflammatory joint disease other than radiographic axial spondyloarthritis (r-axSpA) (such as, but not limited to, rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis (PsA), systemic sclerosis, myositis, etc,), or any other conditions that may, in the judgment of the investigator, interfere with the assessment of r-axSpA.
- Has a history of cancer (except fully treated nonmelanoma skin cancers or cervical carcinoma in situ after complete surgical removal) and is disease free for <5 years before randomization.
- Is known to be infected with hepatitis B virus (HBV), hepatitis C virus (HCV), or human immunodeficiency virus (HIV)
- Has any active infection including but not limited to: A). Symptomatic infection despite adequate treatment (excluding fungal infections of the nail bed or localized oral herpes). B). Chronic infection requiring ongoing antimicrobial treatment. C). Recent infection with completion of parenteral anti-infectives or oral anti-infectives.
- Has active tuberculosis (TB) or meets TB exclusionary parameters
The study team makes the final eligibility decision.
Where it's taking place
- Korea, Republic of
- Colombia
- Ukraine
- Chile
- Brazil
- China
- Turkey
- Canada
- United Kingdom
- Taiwan
- United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Korea, Republic of; Colombia; Ukraine; Chile; Brazil; China and 5 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.