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A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
EU CTIS ID: 2025-520721-21-00
What this study is testing
To evaluate the safety and efficacy of monotherapy and/or combination therapy for the treatment of moderately to severely active Rheumatoid arthritis.
- Therapeutic exploratory (Phase II)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- At any time prior to the Screening Visit, participant must have been treated for > or = 3 months with at least 1 biologic/targeted synthetic disease-modifying antirheumatic drug (b/tsDMARD) therapy but continued to exhibit active RA, or had to discontinue due to intolerability or toxicity, irrespective of treatment duration. The maximum cap for prior use of b/ tsDMARD is 2.
- Participant must be on a stable dose of methotrexate (MTX)
You likely can't join if
- Participant is taking nonsteroidal anti-inflammatory drugs (NSAIDs), acetaminophen/paracetamol, low-potency opioids (tramadol, codeine, hydrocodone, alone or in combination with acetaminophen), unless they have been on stable doses for ≥ 1 week prior to Baseline Visit; and/or oral corticosteroids (equivalent to ≤ 10 mg/day of prednisone), or inhaled corticosteroids for stable medical conditions unless they have been on stable doses for ≥ 4 weeks prior to Baseline Visit.
- History of any arthritis with onset prior to age 17 years or current diagnosis of inflammatory joint disease other than rheumatoid arthritis.
The study team makes the final eligibility decision.
Where it's taking place
- Canada
- United States
- Korea, Republic of
- Puerto Rico
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Canada; United States; Korea, Republic of; Puerto Rico. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.