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Effectiveness of a Nerve Block in the Back of the Head for Treating Headaches Caused by Bleeding in the Brain
EU CTIS ID: 2025-520619-15-00
What this study is testing
To determine the efficacy of bilateral greater occipital nerve block in the management of headache pain related to SAH
- Therapeutic exploratory (Phase II)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Patients with diffuse or perimesencephalic aSAH admitted to the Semicritical Care Unit or ICU of Hospital de la Santa Creu i Sant Pau.
- Hunt and Hess scale 1-3 (see Annex 3).
- Signed informed consent from the patient or their representative.
You likely can't join if
- Presence of other causes of secondary headache (AVM, space-occupying lesions, etc.).
- Pregnancy or breastfeeding.
- Cardiac conduction disorders: Second- or third-degree atrioventricular block. Arrhythmias with hemodynamic instability.
- Convexity SAH.
- Hunt and Hess scale 4 or 5 (see Annex 3).
- History of allergic reaction to local anesthetic
See the full eligibility criteria
- Patients with diffuse or perimesencephalic aSAH admitted to the Semicritical Care Unit or ICU of Hospital de la Santa Creu i Sant Pau.
- Hunt and Hess scale 1-3 (see Annex 3).
- Signed informed consent from the patient or their representative.
- Presence of other causes of secondary headache (AVM, space-occupying lesions, etc.).
- Pregnancy or breastfeeding.
- Cardiac conduction disorders: Second- or third-degree atrioventricular block. Arrhythmias with hemodynamic instability.
- Convexity SAH.
- Hunt and Hess scale 4 or 5 (see Annex 3).
- History of allergic reaction to local anesthetic
- Severe functional dependence (mRS 4-5, see Annex 7).
- GCS ≤8 prior to the procedure (see Annex 4).
- Intracranial surgery ≤1 month prior or planned during hospitalization (excluding ventricular drains).
- Known terminal illness or imminent limitation of therapeutic effort.
- Difficulty or foreseeable loss of clinical follow-up.
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.