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Frostbite Treatment Study comparing tPA and iloprost therapy
EU CTIS ID: 2024-520291-10-01
What this study is testing
To randomize into 2 groups all severe cases of frostbite to be treated with iloprost or tPA as non-inferiority trial. Prospective data will be collected and clinical outcome recorded. The aim is to accrue at least 50 patients and review rates and levels of distal extremity amputations as well as long-term functional outcome. Furthermore various haematological variables will be recorded prior to and after treatment.
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Severe distal extremity frostbite
You likely can't join if
- Contraindications to either tPA or iloprost therapy, less than 18 years age, non-severe frostbite
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.