Authorised Phase I and Phase II (Integrated)- Other Cerebrospinal fluid circulation disorder seen in clinically suspected idiopathic normal pressure hydrocephalus, Alzheimers Disease and healthy controls.

MRI contrast agent in the spinal canal to investigate transportation of the cerebrospinal fluid in the brain.

Q: Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Q: Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

Q: How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Q: Who can join this trial?

This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.

EU CTIS ID: 2024-520146-33-00

What this study is testing

To quantify the distribution and rate of elimination of the contrast agent as assessed by repeated MRI in humans. We will also document any adverse events related to the administration of Gadovist

Phase I and Phase II (Integrated)- Other

A plain-language read of the study's public EU CTIS listing. The study team confirms the details.

Who can take part

You may be able to join if

Patients investigated for suspected idiopathic normal pressure hydrocephalus at Umeå University hospital
Patients with Alzheimers disease.
Healthy controls

You likely can't join if

Age <65 for INPH. Age <55 years for AD and HC
Mini mental state examination (MMSE) < 20
Liver failure
Not able to understand instructions needed for informed concent
known contradicting allergies
Known contraindications for magnetic reconance imaging

See the full eligibility criteria

Who can join

Patients investigated for suspected idiopathic normal pressure hydrocephalus at Umeå University hospital
Patients with Alzheimers disease.
Healthy controls

What rules you out

Age <65 for INPH. Age <55 years for AD and HC
Mini mental state examination (MMSE) < 20
Liver failure
Not able to understand instructions needed for informed concent
known contradicting allergies
Known contraindications for magnetic reconance imaging
Renal impairment (as deffined by blood test at admission)
Current treatment with anticoagulation medication
Low threshold for seizures
History of bronchial asthma
Previous investigation with gadolinium contrast medium

The study team makes the final eligibility decision.

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.

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BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.