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Estrogen replacement therapy (ERT) for treatment of adolescent anorexia nervosa – An open label study
EU CTIS ID: 2024-519908-27-01
What this study is testing
The present project is a pilot study that aim to test the efficacy and feasibility of estrogen replacement therapy on psychological and physiological symptoms in girls with anorexia nervosa. Hence, if this pilot study shows results that the estrogen replacement treatment is feasible and the included patients show an improvement in anorectic symptoms, we will test this treatment in a full-scale randomized placebo-controlled trial. The pilot study will be performed within the health region of Northern Norway, UNN-HF. The drug that will be tested in the present study is already on the market and used for other purposes. Thus, the implementation of estrogen replacement therapy in clinical practice can therefore easily be performed and will provide options for improved treatment for patients with anorexia. The project fit the scope of the call that define clinical research and translational research as aims.
- Therapeutic exploratory (Phase II)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Patients with anorexia nervosa, and anorexia with concomitant anxiety and depression will be included.
You likely can't join if
- One or more contra indices for use of hormonal contraceptives, hereditary predisposition for venous or arterial thrombosis, any previous unexplained vaginal bleeding, diagnosed or susceptible diabetes mellitus, any cerebrovascular disease, any type of heart failure, any neurological disease or structural brain damage, any past or present episodes of psychosis or mania, any current use of antipsychotic medication, diagnoses of mental retardation (F70-F79), pregnancy, past or present substance abuse.
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 0-17 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.