Randomized, double-blind, parallel group clinical trial to evaluate the efficacy and safety of PRGF eye drops as a treatment for dry eye disease in patients with glaucoma

You likely can't join if

• Exclusion criteria of ophthalmic nature in at least one eye 1. Ocular rosacea 2. History of ocular trauma or ocular infection in the previous 3 months. 3. History of ocular allergy 4. History of uveitis (last episode less than 6 months). 5. History of inflammatory corneal ulcer in the last 12 months. 6. Ocular surgery in the previous 3 months or foreseen indication for ocular surgery during the duration of the study.
• Systemic/non-ophthalmic exclusion criteria 7. Known or suspected hypersensitivity to one of the components of the investigational product or ancillary products. 8. History of any active systemic condition incompatible with the investigation or which, in the investigator's judgment, may interfere with the results of the investigation or with patient safety 9. Active allergic rhinitis or allergic rhinitis likely to reactivate during the investigation. 10. Any other medical or surgical history, disorder or disease likely to require or modify systemic medication during the investigation (systemic medication must be stable in the three months prior to screening).
• Exclusion criteria specifically related to women of childbearing potential 11. Pregnancy or breastfeeding 12. Women of childbearing age who are not using reliable contraceptive methods (oral contraceptives, IUD, subdermal contraceptive implants, vaginal ring, patch) and who have not undergone surgical sterilization.
• Exclusion criteria relating to factors of a general nature 13. Inability of the patient to understand the research procedures or to give informed consent. 14. Non-compliance on the part of the patient (e.g., refusal to attend a visit or to complete a questionnaire or study tests); 15. Participation in this trial at the same time as participation in another trial. 16. Participation in this trial during the opt-out period of another trial; 17. 17. Patients who are institutionalized by court or regulatory order, who are confined in psychiatric facilities, correctional institutions, or state institutions, and employees of the sponsor's research facilities or company. 18. Patient not covered by the public health system. 19. Patient under guardianship or court-ordered guardianship. 20. Patients who have used or use a prohibited treatment (or perform a prohibited modification of the therapeutic regimen). 21. Patients diagnosed with coagulopathies or autoimmune diseases, infection or tumor in the area of application, or retinopathy. 22. Patients with hepatic insufficiency.