Authorised Therapeutic use (Phase IV) Major depressive disorder

A randomized controlled trial of the effect of anesthetic dose during electroconvulsive therapy for major depression

EU CTIS ID: 2024-519407-99-00

What this study is testing

The main objective of this trial is to to test if the reduction of depressive symptoms after six electroconvulsive therapy (ECT) sessions is larger in patients anesthetized with a low thiopental dose compared to patients anesthetized with a high thiopental dose during ECT.

  • Therapeutic use (Phase IV)

A plain-language read of the study's public EU CTIS listing. The study team confirms the details.

Who can take part

You may be able to join if

  • • age 18 years and above • hospitalized patients with an ongoing major depressive episode within MDD

You likely can't join if

  • • postpartum depression • schizophrenia • psychotic syndrome • bipolar disorder • patients for whom the anesthesiologist deems that a high anesthetic dose is inappropriate due to a somatic condition. • patients under compulsory psychiatric care according to the Swedish Act on Compulsory Psychiatric Care (Lagen om psykiatrisk tvångsvård) • patients who do not speak or understand Swedish or English sufficiently to provide informed consent or complete study assessments

The study team makes the final eligibility decision.

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.