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A study of IPN10200 for the treatment of cervical dystonia in adults
EU CTIS ID: 2024-519248-34-00
What this study is testing
To assess the efficacy of IPN10200 treatment compared to placebo in reducing Cervical Dystonia (CD) symptoms at Week 4 in adult participants
- Therapeutic exploratory (Phase II)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- A clinical diagnosis of isolated Cervical Dystonia (CD) (idiopathic) characterized by dystonic symptoms localised to the head, neck, and shoulder areas with at least moderate severity at Screening and Baseline (Day 1) defined as: • (a) Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS)- Total score ≥20 • (b) TWSTRS-Severity subscale score ≥15 • (c) TWSTRS-Disability subscale score ≥3 • (d) TWSTRS-Pain subscale score ≥ 1
- Treatment naïve or non-naïve to BoNT therapy for CD
You likely can't join if
- Participants presenting with a swallowing disorder of any origin which might be exacerbated by BoNT treatment, such as: • (a) Grade 3 or 4 on the Dysphagia Severity Scale (severe dysphagia) with swallowing difficulties and requiring a change in diet.
- Predominant anterocollis.
- Predominant retrocollis.
- Traumatic torticollis or tardive torticollis.
- Marked limitation on passive range of motion that suggests cervical contractures or structural abnormality.
The study team makes the final eligibility decision.
Where it's taking place
- United States
- United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include United States; United Kingdom. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.