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Methadone for post-operative pain reduction in heart surgery
EU CTIS ID: 2024-519224-24-00
What this study is testing
The primary objective of this trial is to investigate the efficacy of a single‐dose of Intraoperative methadone, administered after induction of anesthesia, compared to administration of fentanil and oxycodone per-operatively (usual care), on the endpoint postoperative opioid consumption in adult subjects undergoing elective or subacute CABG and/or valve surgery.
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- 1) Age ≥ 18 years 2) Scheduled for CABG and/or valve surgery.
You likely can't join if
- 1) Acute surgery 2) Pregnancy or currently breastfeeding 3) Know elongated Qt syndrome 4) Prolonged QT‐interval assessed by electrocardiogram > 500ms 5) Existing treatment with methadone 6) Preadmission treatment with opioids 7) Allergy to methadone 8) Inability to provide informed consent 9) Dialysis There will be no general restrictions on inclusion into other
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.