Authorised Therapeutic use (Phase IV) The trial is about comparing the efficacy of Plenvu with Picoprep. Both are bowel cleansing agents prior to colonoscopy. The patients to be examined are all referred to exclude colorectal cancer disease. The cleansing process is not directly related to treatment of these patients but have an effect on the visualisation of the mucosa of the bowel and thus the quality of the colonoscopy.

A trial to compare efficacy and tolerability of Plenvu® and Picoprep® as cleansing agents of the large bowel before colonoscopy (examination of the bowel with a fiberoptic device)

EU CTIS ID: 2024-518544-21-00

What this study is testing

Aim of the study is to compare the efficacy and tolerability of the relatively new bowel preparation Plenvu® with the well established bowel preparation Picoprep® as cleansing agents before colonoscopy. This is to test whether the low volume Polyethylin Glycol-electrolytes lavage solution preparation Plenvu® would have non-inferior efficacy on bowel preparation compared with Picosulfate based Picoprep® with a better effect on compliance and tolerability.

  • Therapeutic use (Phase IV)

A plain-language read of the study's public EU CTIS listing. The study team confirms the details.

Who can take part

You may be able to join if

  • Ambulant colonoscopy
  • Older than18

You likely can't join if

  • Younger than 18
  • Patients with Phenylketonuria
  • Patients with Glucose-6-phosphate-dehydrogenase deficiency
  • Patients with rectum and/or colon resections
  • Known with severe heart failure
  • Known with severe renal failure (eGFR<30)*
See the full eligibility criteria
Who can join
  • Ambulant colonoscopy
  • Older than18
What rules you out
  • Younger than 18
  • Patients with Phenylketonuria
  • Patients with Glucose-6-phosphate-dehydrogenase deficiency
  • Patients with rectum and/or colon resections
  • Known with severe heart failure
  • Known with severe renal failure (eGFR<30)*
  • Known with colonic stenosis
  • Pregnant or breastfeeding
  • Acute colonoscopy
  • Cancer screening program colonoscopy
  • Mentally retarded
  • Redo colonoscopy of patients included in this study and colonoscopy was canceled because of bad bowel preparation.

The study team makes the final eligibility decision.

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.

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BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.