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Clinical Trial To Determine The Effectiveness And Safety Of Topical Insulin In Dry Eye
EU CTIS ID: 2024-518376-31-00
What this study is testing
The main objective is to investigate the efficacy of the use of insulin eye drops in the control of moderate-severe dry eye disease.
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Patients older than 18 years
- Dry eye disease diagnosis
- Treatment with artificial tears or hyaluronic acid gels for at least 3 months
- Signed informed consent by the patient
- Staining equal to or greater than Oxford II
You likely can't join if
- Under 18 years old
- Treatment for dry eye disease other than artificial tears or hyaluronic acid gels
- Severe dry eye disease that requires immediate treatment
- Eye surgery in the last 6 months
- Other concomitant corneal pathology: cicatricial diseases of the ocular surface, uveitis, ocular infection in the last 90 days, trauma in the last 90 days
- Contact lenses
See the full eligibility criteria
- Patients older than 18 years
- Dry eye disease diagnosis
- Treatment with artificial tears or hyaluronic acid gels for at least 3 months
- Signed informed consent by the patient
- Staining equal to or greater than Oxford II
- Under 18 years old
- Treatment for dry eye disease other than artificial tears or hyaluronic acid gels
- Severe dry eye disease that requires immediate treatment
- Eye surgery in the last 6 months
- Other concomitant corneal pathology: cicatricial diseases of the ocular surface, uveitis, ocular infection in the last 90 days, trauma in the last 90 days
- Contact lenses
- Visual acuity less than 0.1
- Changes in topical treatment in the past 3 months
- Eyelid alterations: eyelid malposition, drainage alterations nasolacrimal or blink disorders
- Other topical treatment other than artificial tears and/or hyaluronic acid gel
- Allergy or intolerance to any of the components included in the study
- Modifications in systemic immunosuppressive treatment
- Pregnancy or lactation
- Women of childbearing age who do not use a highly effective contraceptive method
- History of alcohol or drug abuse
- Participation in another clinical trial in the last 30 days
- Systemic pathology (cardiopulmonary pathology, connective tissue disorders, neurological or psychiatric pathology) or baseline situation of the patient that does not allow the examination (such as mental or psychomotor retardation)
- Corneal staining under Oxford II
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.