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Ketamine therapy in obsessive-compulsive disorder and its effects on neuropsychological function under stress in a cross-over trial
EU CTIS ID: 2024-518212-40-00
What this study is testing
Test the efficacy of ketamine in obsessive-compulsive disorder
- Therapeutic confirmatory (Phase III)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Primary diagnosis of obsessive-compulsive disorder
- A score of 16 or higher on the Yale-Brown Obsessive- Compulsive Scale
- Age of at least 18 years and ability to provide written informed consent
- At least one previous treatment for OCD
You likely can't join if
- Any history of current or past psychotic disorder
- Untreated hyperthyroidism
- Untreated disorders severely affecting the HPA-axis (M.Addison, M.Cushing)
- Current pharmacological therapy severely affecting the HPA- axis like corticosteroids or ACTH
- Inability to follow the study protocol or adhere to operational requirements
- A manic episode within the preceding three years
See the full eligibility criteria
- Primary diagnosis of obsessive-compulsive disorder
- A score of 16 or higher on the Yale-Brown Obsessive- Compulsive Scale
- Age of at least 18 years and ability to provide written informed consent
- At least one previous treatment for OCD
- Any history of current or past psychotic disorder
- Untreated hyperthyroidism
- Untreated disorders severely affecting the HPA-axis (M.Addison, M.Cushing)
- Current pharmacological therapy severely affecting the HPA- axis like corticosteroids or ACTH
- Inability to follow the study protocol or adhere to operational requirements
- A manic episode within the preceding three years
- Current or unstable remitted substance abuse or dependence except nicotine
- Pregnancy or elevated risk of becoming pregnant during study duration (desire to have children) and refusal to utilize a proper method of contraception
- Any current severe personality disorder except comorbid anankastic personality disorder
- Current unstable suicidality
- Morbus Raynaud
- Unstable hypertension
- Any other severe and unstable cardiovascular disease -
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.