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Oxytocin versus Prostaglandins for labor Induction of women with an unfavorable Cervix after 24 hours of cervical ripening: a multicenter non inferiority randomized trial
EU CTIS ID: 2024-517675-20-00
What this study is testing
To show that, among women with an unfavorable cervix after a first cervical ripening, induction of labor with oxytocin is not associated with an increased risk of caesarean delivery in comparison with repeating cervical ripening with prostaglandins.
- Phase III and phase IV (Integrated)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Pregnant woman
- ≥ 18 years old
- With a singleton cephalic pregnancy
- At a term ≥37+0 weeks of gestation
- Gestational age estimated from the first trimester ultrasound (realized between 11+0 and 13+6 weeks of gestation)
- With a medical indication of labor with a previous pharmacological or mechanical cervical ripening of 24 hours
You likely can't join if
- Any measures of legal protection
- Prior caesarean section or uterine scar
- Contra-indications to a vaginal delivery
- Foetus with suspected severe congenital abnormalities
- Pathological foetal heart rate
- Contra-indications to prostaglandins (ANGUSTA®, PROPESS®, PROSTINE®)
See the full eligibility criteria
- Pregnant woman
- ≥ 18 years old
- With a singleton cephalic pregnancy
- At a term ≥37+0 weeks of gestation
- Gestational age estimated from the first trimester ultrasound (realized between 11+0 and 13+6 weeks of gestation)
- With a medical indication of labor with a previous pharmacological or mechanical cervical ripening of 24 hours
- Bishop score ≤ 6 at inclusion (unfavorable cervix)
- Written informed consent
- French health insurance policy holder
- Any measures of legal protection
- Prior caesarean section or uterine scar
- Contra-indications to a vaginal delivery
- Foetus with suspected severe congenital abnormalities
- Pathological foetal heart rate
- Contra-indications to prostaglandins (ANGUSTA®, PROPESS®, PROSTINE®)
- Contra-indications for using oxytocin
- Woman in labor
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.