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A clinical study of raludotatug deruxtecan in people with gastrointestinal cancers (MK-5909-005)
EU CTIS ID: 2024-517416-30-00
What this study is testing
1. To evaluate the confirmed ORR per RECIST 1.1 as assessed by BICR
- Phase II and Phase III (Integrated)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Has one of the following cancers: • Unresectable or metastatic pancreatic ductal adenocarcinoma (PDAC); • Unresectable or metastatic adenocarcinoma of the biliary tract [intra- or extrahepatic cholangiocarcinoma (CCA) or gallbladder cancer (GBC)]; • Unresectable or metastatic colorectal adenocarcinoma; • unresectable or metastatic gastric adenocarcinoma, gastroesophageal junction adenocarcinoma (GEJAC), or esophageal adenocarcinoma (EAC)
- Has received prior therapy for the cancer
- Has a life expectancy of at least 3 months
You likely can't join if
- Has a history of (noninfectious) interstitial lung disease (ILD)/pneumonitis that required steroids or has current ILD/pneumonitis, and/or suspected ILD/pneumonitis
- Has clinically severe pulmonary compromise resulting from intercurrent pulmonary illnesses
- Has uncontrolled or significant cardiovascular disease
- Has a known additional malignancy that is progressing or has required active treatment within the past 3 years
- Has known active central nervous system (CNS) metastases and/or carcinomatous meningitis
- Has not adequately recovered from major surgery or has ongoing surgical complications
The study team makes the final eligibility decision.
Where it's taking place
- Taiwan
- Hong Kong
- Canada
- Switzerland
- United States
- Argentina
- Chile
- Thailand
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Taiwan; Hong Kong; Canada; Switzerland; United States; Argentina and 2 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.