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Pain medication tapering for chronic low back pain patients, treated with an intervention focusing on pain relief for axial problems.
EU CTIS ID: 2024-516647-79-00
What this study is testing
The primary objective of the study is to examine whether there is a difference in disability 12 months after an intervention focusing on pain relief for axial pain in patients with chronic lower back pain after receiving a standardized pain medication tapering protocol before the intervention, a personalized pain medication tapering protocol before the intervention, or no pain medication tapering protocol before the intervention.
- Phase III and phase IV (Integrated)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Patients being diagnosed with chronic lower back pain, defined as patients with lower back pain for more than three months. Patients need to be scheduled for a non-pharmacological intervention focusing on pain relief axial problems (such as spinal cord stimulation, dorsal root ganglion stimulation, radiofrequency ablation, infiltrations, epidural injections, nerve blocks, revalidation or kinesitherapy, psychological treatments (such as pain education, cognitive behavioural therapy, mindfulness, and acceptance and commitment therapy), or adjunctive therapies) to be eligible for participation in the study. Moreover, patients must be 18 years or older, taking opioids, and be able to speak and read Dutch or French.
You likely can't join if
- Exclusion criteria include the following: Being actively treated for cancer, Having a life expectancy below 6 months, Receiving intrathecal drug delivery, Having contraindications for Clonidine (e.g., known hypotension which requires medication) or for Buprenorphine/Naloxone (e.g., severe respiratory insufficiency, hepatic insufficiency), Having epilepsy currently treated by Pregabalin, Currently using benzodiazepines at doses more than 40 mg diazepam-equivalents per day.
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.