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Preservation of Fertility by Ovarian Stimulation Associated With Tamoxifen, Prior Chemotherapy for Breast Cancer (PRESAGE)
EU CTIS ID: 2024-516282-37-00
What this study is testing
To assess the feasibility of ovarian stimulation combining Tamoxifen with recombinant FSH followed by oocyte vitrification and/or embryo freezing prior to chemotherapy for breast cancer
- Therapeutic exploratory (Phase II)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- 1. Obtaining signed informed consent prior to any trial-specific procedure
- 10. Social protection
- 2. Between 18 and 40 yo
- 3. Histologically proven invasive breast carcinoma
- 4. Indication for adjuvant or neoadjuvant chemotherapy validated by pre-therapy PCR
- 5. T0-T1-T2-T3
You likely can't join if
- 1. Previous breast cancer
- 2. History of any other cancer in the last 5 years, with the exception of basal cell and squamous cell skin cancers
- 3. Pregnancy in progress
- 4. Pulmonary embolism less than 6 months old
- 5. Deep vein thrombosis less than 6 months old
- 6. Dementia or altered mental state
See the full eligibility criteria
- 1. Obtaining signed informed consent prior to any trial-specific procedure
- 10. Social protection
- 2. Between 18 and 40 yo
- 3. Histologically proven invasive breast carcinoma
- 4. Indication for adjuvant or neoadjuvant chemotherapy validated by pre-therapy PCR
- 5. T0-T1-T2-T3
- 6. N0-N1-N2a
- 7. M0 after extension assessment according to French INCa recommendations
- 8. AMH (anti-müllerian hormone) ≥1 ng/mL and/or AFC (antral follicle count) ≥ 5 (on ultrasound: ovaries puncturable transvaginally),
- 9. HIV serology negative
- 1. Previous breast cancer
- 2. History of any other cancer in the last 5 years, with the exception of basal cell and squamous cell skin cancers
- 3. Pregnancy in progress
- 4. Pulmonary embolism less than 6 months old
- 5. Deep vein thrombosis less than 6 months old
- 6. Dementia or altered mental state
- 7. Legal incapacity or limited legal capacity. Medical or psychological conditions preventing the subject from understanding the study and signing the consent form (art. L.1121-6, L.1211-8, L.1211-9).
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.