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Randomised, double-blind study comparing the analgesic efficacy of a lidocaine-prilocaine combination with lidocaine alone as local anesthesia for dental procedures in participants with MC1R mutation
EU CTIS ID: 2024-515965-32-00
What this study is testing
To investigate the analgesic efficacy of a lidocaine-prilocaine combination compared to lidocaine alone in dental procedures.
- Therapeutic exploratory (Phase II)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Participants aged ≥18 and ≤ 65.
- Written informed consent to participate in the study.
- Participants with red hair or with at least one parent and/or grandparent with red hair and/or genetic sibling from same parents with red hair.
You likely can't join if
- History or presence of hypersensitivity or allergy to lidocaine (or prilocaine or other local anesthetics (amid type or sodium metabisulfite), a history of anaphylactic or anaphylactoid reactions, or a history of other allergy that, in the opinion of the investigator, contraindicates participation.
- Participants with known thyrotoxicosis.
- Participants with severe heart disease, including tachycardia.
- Local infection in the area of injection.
- Participants with congenital or idiopathic methemoglobinemia.
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.