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Multicentre Randomized trial of Ghrelin in anterior circulation ischemic stroke treated with endovascular thrombectomy. A randomized phase 2 trial.
EU CTIS ID: 2024-515705-26-00
What this study is testing
The primary objective of this study is to assess the effect of ghrelin on the severity of the neurological deficit at seven days after symptom onset in patients with acute ischemic stroke caused by large vessel occlusion of the anterior circulation and treated with EVT.
- Therapeutic exploratory (Phase II)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- a clinical diagnosis of acute ischemic stroke, caused by intracranial large vessel occlusion of the anterior circulation (distal intracranial carotid artery or middle (M1/proximal M2) cerebral artery) confirmed by neuro-imaging (CTA or MRA)
- treatment with EVT, defined as groin puncture in the angio suite
- CT or MRI ruling out intracranial hemorrhage
- a pre-EVT score of at least 10 on the NIHSS
- age of 18 years or older
- written informed consent (deferred)
You likely can't join if
- pre-stroke disability defined as mRS ≥ 2
- life expectancy shorter than one year
- child-bearing potential
See the full eligibility criteria
- a clinical diagnosis of acute ischemic stroke, caused by intracranial large vessel occlusion of the anterior circulation (distal intracranial carotid artery or middle (M1/proximal M2) cerebral artery) confirmed by neuro-imaging (CTA or MRA)
- treatment with EVT, defined as groin puncture in the angio suite
- CT or MRI ruling out intracranial hemorrhage
- a pre-EVT score of at least 10 on the NIHSS
- age of 18 years or older
- written informed consent (deferred)
- possibility to start trial treatment within 6 hours of stroke onset
- pre-stroke disability defined as mRS ≥ 2
- life expectancy shorter than one year
- child-bearing potential
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.