BridgeMD
Impact of Exercise and Mediterranean diet vs Aspirin on live-birth rate and cardiovascular programming in In Vitro Fertilization (MEDITATE-IVF): a Randomized Study.
EU CTIS ID: 2024-515590-10-00
What this study is testing
To evaluate the impact of exercise and the Mediterranean diet vs. aspirin, or no intervention, prior to in vitro fertilization, on the cumulative live birth rate.
- Therapeutic confirmatory (Phase III)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Patients with primary infertility justifying IVF treatment, who wish to become pregnant, > 18 years of age, candidates for single embryo transfer in day 5, who give written consent when invited to participate in the study protocol
You likely can't join if
- Pregnancy at the moment of inclusion, presence of comorbidities that contraindicate IVF, pregnancy or childbirth, known allergies to any of the interventions to be applied, probability of loss to follow-up, probability of delivery in another hospital or center.
- Patients with conditions where LDA administration is contraindicated will also be excluded; some of these conditions or comorbidities would also contraindicate IVF. · Allergy to acetylsalicylic acid or any of the other components. · Gastric ulcer, duodenal or recurrent gastric symptoms. · Allergic asthmatic reactions when taking anti-inflammatories, acetylsalicylic acid, other analgesics, as well as the dye tartrazine. · Hemophilia or other blood clotting problems that predispose to bleeding. · Severe kidney and / or liver failure. · Asthmatic crises, with or without nasal polyps, after ingestion of acetylsalicylic acid. · Diagnosis of glucose-6-phosphate dehydrogenase deficiency. · Treatment with oral anticoagulants. · Treatment with anti-inflammatories or other types of drugs that can interact with LDA. · Hypertension treated with diuretics and angiotensin converting enzyme (ACE) inhibitors.
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.