BridgeMD
MERCURI-2
EU CTIS ID: 2024-515260-31-00
What this study is testing
Prevent AKI
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- > 18 years-old
- Undergoing elective cardiac surgery with cardio-pulmonary bypass (CPB) or off-pump coronary artery bypass surgery (OPCAB).
- Providing informed consent
You likely can't join if
- Current treatment with SGLT2 inhibitors
- Reduced kidney function at baseline with eGFR < 20 ml/min at time of inclusion
- Diabetes Mellitus Type 1
- History of diabetic keto acidosis
- Diabetes Mellitus Type 2 with BMI<25 for people with type 2 diabetes who are using multiple daily insulin injections (both short and long-acting insulin)
- Systolic blood pressure < 100 mmHg at time of inclusion
See the full eligibility criteria
- > 18 years-old
- Undergoing elective cardiac surgery with cardio-pulmonary bypass (CPB) or off-pump coronary artery bypass surgery (OPCAB).
- Providing informed consent
- Current treatment with SGLT2 inhibitors
- Reduced kidney function at baseline with eGFR < 20 ml/min at time of inclusion
- Diabetes Mellitus Type 1
- History of diabetic keto acidosis
- Diabetes Mellitus Type 2 with BMI<25 for people with type 2 diabetes who are using multiple daily insulin injections (both short and long-acting insulin)
- Systolic blood pressure < 100 mmHg at time of inclusion
- Emergency surgery, defined as in need of surgery for medical reasons < 7 days, i.e. “S1- 4” according to the Amsterdam UMC classification
- Female of child-bearing potential who is pregnant, breast-feeding or intend to become pregnant or is not using adequate contraceptive methods
- Known or suspected allergy to trial products or other drugs in the same class
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.