BridgeMD
Characterization of antibodies in the nose after influenza vaccination
EU CTIS ID: 2024-513981-21-00
What this study is testing
The proposed study aims to investigate the quantitative and qualitative differences in antibody responses between intranasal and intramuscular vaccination with the influenza vaccine.
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Participants between 18 and 40 years old
- Male and female sex
- Participants that are generally healthy without substantial comorbidities, especially no primary or secondary immunodeficiencies
You likely can't join if
- Previous influenza vaccination < 4 months before the study
- Breastfeeding during the course of the study
- Known chicken-egg allergy
- Known hypersensitivity to any other of the vaccine components
- Use of anticoagulants
- Use of oral corticosteroids or antibiotics in the past 6 weeks
See the full eligibility criteria
- Participants between 18 and 40 years old
- Male and female sex
- Participants that are generally healthy without substantial comorbidities, especially no primary or secondary immunodeficiencies
- Previous influenza vaccination < 4 months before the study
- Breastfeeding during the course of the study
- Known chicken-egg allergy
- Known hypersensitivity to any other of the vaccine components
- Use of anticoagulants
- Use of oral corticosteroids or antibiotics in the past 6 weeks
- Diagnosed with chronic rhinosinusitis, allergic rhinitis and or allergic asthma
- A condition that requires salicylate treatment
- Previous influenza infection < 4 months before the study
- Vaccinations with other vaccines <2 months before inclusion
- Incompetence to provide informed consent prior or during study
- History of severe nose bleedings
- Symptoms of a respiratory tract infection or common cold in the past 2 weeks
- Documented primary or secondary immunodeficiencies and individuals using methotrexate
- Daily smoking (including vapes) for at least one consecutive month in the last 2 year
- Pregnancy during the time of the study
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.