Authorised Therapeutic use (Phase IV) Glioblastoma multiforme

Brain cancer and changes in immune system

EU CTIS ID: 2024-512136-30-00

What this study is testing

An open label, Phase IV study to assess immunological changes in patients with glioblastoma multiforme treated with bevacizumab infusion

  • Therapeutic use (Phase IV)

A plain-language read of the study's public EU CTIS listing. The study team confirms the details.

Who can take part

You may be able to join if

  •  Not recurrent glioblastoma multiforme patients (either after opus or with no opus) before radiotherapy and temozolomide therapy.  Recurrent patients who have already undergone other therapeutic intervention (surgery, radiotherapy and temozolomide therapy) and due to the recurrence of the disease, based on clinical experience, it is justified to start bevacizumab therapy.  Known relapse patients who are already receiving bevacizumab therapy.

You likely can't join if

  •  Unwillingness to sign the written Informed Consent Form.  History of psychiatric diseases and treatment.  Hypersensitivity to the active substance or to any of the excipients.  Hypersensitivity to Chinese Hamster Ovary (CHO) cell products or other recombinant human or humanised antibodies.  Participation in another clinical trial within 3 months prior to this study.  Known drug or chronic alcohol abuse, drug addiction.  Malignant disease other than GBM.  Legal incapacity and/or other circumstances rendering the subject unable to understand the nature, scope and possible consequences of the study.  Evidence of an uncooperative attitude.  Vulnerable subject.

The study team makes the final eligibility decision.

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.