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Interest of Intra-nodal injection of gentamicin for the treatment of suppurated cat scratch disease's lymphadenitis
EU CTIS ID: 2024-512037-32-00
What this study is testing
To compare the effect of an intra-nodal injection of gentamicin versus placebo on the outcome at 28 days in patients with suppurative cat scratch disease's lymphadenitis treated with oral azithromycin.
- Therapeutic confirmatory (Phase III)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Adults ≥18 years old
- Informed consent
- Suppurated cat-scratch disease’s adenitis: Suppurated form of adenitis confirmed by echography and serology positive for IgG and/or IgM against B. henselae
- Affiliation to the French Social Security System
You likely can't join if
- Suppurated adenitis non related to cat scratch disease
- Patient taking a prohibited study treatment
- Legal protection regime for adults
- Non-suppurated cat scratch disease’s adenitis
- Suppurated cat scratch disease’s adenitis already fistulized
- Suspected visceral B. henselae infection (neurologic or ophthalmic symptoms, hepato-splenic or valvular involvement confirmed by echography)
See the full eligibility criteria
- Adults ≥18 years old
- Informed consent
- Suppurated cat-scratch disease’s adenitis: Suppurated form of adenitis confirmed by echography and serology positive for IgG and/or IgM against B. henselae
- Affiliation to the French Social Security System
- Suppurated adenitis non related to cat scratch disease
- Patient taking a prohibited study treatment
- Legal protection regime for adults
- Non-suppurated cat scratch disease’s adenitis
- Suppurated cat scratch disease’s adenitis already fistulized
- Suspected visceral B. henselae infection (neurologic or ophthalmic symptoms, hepato-splenic or valvular involvement confirmed by echography)
- Immunodepression (except diabetes)
- Pregnancy
- Contraindication to pus aspiration from lymphadenitis (history of bleeding or patient taking curative anticoagulation therapy or platelet count < 50.000/mm3)
- Contraindication to azithromycin (history of QT interval prolongation, history of liver toxicity of hypersensitivity to macrolides or treatment with ergotamine, dihyroergotamine, bepridil, cisapride, pimozide, mizolastine or colchicine) or to aminoglycosids (myasthenia, history of hypersensitivity to aminoglycosides)
- Patient with a contraindication to aminoglycosides (myasthenia gravis, history of hypersensitivity to aminoglycosides)
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.