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Benefits of inhalation of 7% hypertonic saline solution prior to ELTGOL physiotherapy, in patients with bronchiectasis. A randomized controlled trial.
EU CTIS ID: 2024-511677-29-01
What this study is testing
To evaluate the effect of the combination of once-daily 7% hypertonic saline and twice-daily ELTGOL technique in mucus clearance in patients with bronchiectasis compared both to once-daily isotonic saline and twice-daily ELTGOL technique and to twice-daily ELTGOL technique on its own
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Men and woman ≥ 18 years old
- Bronchiectasis confirmed by high resolution computed tomography
- no exacerbations in the previous month
- chronic purulent sputum ( ≥10ml daily expectoration)
- at least one exacerbation in the previous year
- FEV1 ≥30% after bronchodilation
You likely can't join if
- patients > 85 years old
- asthma, allergic bronchopulmonary aspergillosis or cystic fibrosis
- current smokers or a smoking history of ≥20 pack/year
- following mucoactive treatment in the previous month
- contraindications to perform ELTGOL, spirometry or to attend visits
- pulmonary rehabilitation in the previous 6 months
See the full eligibility criteria
- Men and woman ≥ 18 years old
- Bronchiectasis confirmed by high resolution computed tomography
- no exacerbations in the previous month
- chronic purulent sputum ( ≥10ml daily expectoration)
- at least one exacerbation in the previous year
- FEV1 ≥30% after bronchodilation
- sign the informed consent
- patients > 85 years old
- asthma, allergic bronchopulmonary aspergillosis or cystic fibrosis
- current smokers or a smoking history of ≥20 pack/year
- following mucoactive treatment in the previous month
- contraindications to perform ELTGOL, spirometry or to attend visits
- pulmonary rehabilitation in the previous 6 months
- change of treatment the previous month
- uncontrolled hypertension
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.