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Local Levobupivacaine for pain reflief after esophageal ESD
EU CTIS ID: 2024-510912-66-00
What this study is testing
To evaluate the efficacy of local injection of levobupivacaine during esophageal ESD for direct post-procedural pain relief (within 90 minutes after ESD).
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- - Patients age ≥18 years at time of consent
- - Visible lesion in the esophagus, minimum diameter of the lesion ≥20 mm
- - Scheduled for esophageal ESD
- - Informed consent
You likely can't join if
- - Presence of multiple lesions requiring two or more separate endoscopic resections
- - Allergy to LB or other amide-type local anaesthesia
- - Current regular use of opioids
- - Other aetiology causing pain similar to post-ESD pain
- - Pregnancy or breast feeding
- - Inability to assess pain due to severe psychiatric or neurological disease
See the full eligibility criteria
- - Patients age ≥18 years at time of consent
- - Visible lesion in the esophagus, minimum diameter of the lesion ≥20 mm
- - Scheduled for esophageal ESD
- - Informed consent
- - Presence of multiple lesions requiring two or more separate endoscopic resections
- - Allergy to LB or other amide-type local anaesthesia
- - Current regular use of opioids
- - Other aetiology causing pain similar to post-ESD pain
- - Pregnancy or breast feeding
- - Inability to assess pain due to severe psychiatric or neurological disease
- - Insufficient command of Dutch language
- - History of esophageal surgery other than fundoplications
- - History of esophageal ablation therapy
- - History of radiotherapy of the esophagus
- - Esophageal varices
- - Prior endoscopic resection in the same area
- - Brugada syndrome
- - Uncontrolled coagulopathy
- - Severe medical comorbidities precluding endoscopy
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.