A study on the immune response and safety of vaccine against respiratory syncytial virus given to adults 18 to 49 years of age at increased risk for respiratory syncytial virus disease, compared to older adults 60 years of age and above.

You may be able to join if

• "Inclusion criteria for all participants • Participants and/or participant’s parent(s)/LAR who, in the opinion of the investigator, can and will comply with the requirements of the protocol (e.g., completion of the eDiary, attend study site visits, ability to access and utilize a phone or other electronic communications). • Written or witnessed informed consent obtained from the participant/participant’s parent(s)/LAR(s) (participant must be able to understand the informed consent) prior to performance of any study-specific procedure. Written informed assent obtained from the participant (participant must be able to understand the informed assent) if he/she is less than the legal age* prior to performance of any study-specific procedure. "
• "Inclusion criteria for all participants of Cohort 1 and Cohort 3 • A male or female participant 18-49 YOA at the time of the study intervention administration. • Participants should be diagnosed with at least 1 of the following medical conditions if considered medically stable by the investigator: (A stable condition is defined as a disease not requiring significant change (based on the investigator’s opinion) in therapy or worsening during the 3 months before enrollment.) • Chronic cardiopulmonary disease resulting in activity restricting symptoms or use of long‑term medication: o Chronic obstructive pulmonary disease (COPD) - Global Initiative for Chronic Obstructive Lung Disease (GOLD) Grade 2-4 o Asthma - Patient on Maintenance and Reliever Therapy (MART) OR with at least one rescue treatment per week (excluding exercise asthma) o Cystic fibrosis o Other chronic respiratory diseases: lung fibrosis, restrictive lung disease, interstitial lung disease, emphysema or bronchiectasis o Chronic heart failure - A minimum of class II symptoms according to New York Heart Association classification of heart failure o Pre-existing CAD (CAD not otherwise specified) - Physician diagnosis of CAD based on electrocardiogram, exercise stress test, nuclear stress test, cardiac computed tomography scan or cardiac angiogram (more than the presence of hypercholesterolemia) o Cardiac arrhythmia - Patient diagnosed with a cardiac arrythmia that require medical support either pharmacologically or with a medical device - Diabetes mellitus: types 1 or 2 with active treatment for the past 6 months - Other diseases at increased risk for RSV disease o Chronic kidney disease - G2-G3 disease (Glomerular Filtration Rate between 30 and 90 ml/min/1.73 m2) o Chronic moderate to severe liver disease o Neurologic or neuromuscular conditions • Female participants of non-childbearing potential may be enrolled in the study. • Female participants of childbearing potential may be enrolled in the study, if the participant: - has practiced adequate contraception from 1 month prior to study intervention administration, and - has a negative pregnancy test on the day of study prior to intervention administration, and - has agreed to continue adequate contraception for at least 1 month after completion of the study intervention administration. "
• "Inclusion criteria for all participants of Cohort 2 A male or female participant >60 YOA at the time of the study intervention administration. • Participants with chronic stable medical conditions with or without specific treatment, such as diabetes, hypertension or cardiac disease are allowed to participate in this study if considered medically stable by the investigator. (A stable condition is defined as a disease not requiring significant change (based on the investigator’s opinion) in therapy or worsening during the 3 months before enrollment.) • Participants living in the general community or in an assisted-living facility that provides minimal assistance, such that the participant is primarily responsible for self-care and activities of daily living. "