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Randomized and controlled clinical trial of the efficacy and safety of the use of lidocaine and magnesium sulfate for lung resection surgery using Video-Assisted Thoracic Surgery (VATS)
EU CTIS ID: 2023-509503-33-00
What this study is testing
To analyze whether the intravenous administration of lidocaine and magnesium sulfate during the intraoperative period of patients with lung resection using VATS reduces morphine consumption in the first 24 postoperative hours.
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Patients undergoing lung tumor resection surgery using video-assisted thoracoscopy.
- The patient must be 18 years of age or older.
- The patient, or his or her representative, has given consent to participate in the study.
- The patient must, in the opinion of the investigator, be able to comply with all the requirements of the clinical trial.
You likely can't join if
- Patients who have previously been diagnosed with chronic pain prior to surgery.
- Patients unable to clearly understand the objectives and methodology of the study.
- Patients with chronic kidney damage with glomerular filtration < 60 ml/min (stage III-V).
- Patients with liver dysfunction with total bilirubin > 3mg/dL.
- Expected surgery lasting more than 6 hours or no extubation plan immediately after surgery.
- Patients with < 45kg and > 100kg.
See the full eligibility criteria
- Patients undergoing lung tumor resection surgery using video-assisted thoracoscopy.
- The patient must be 18 years of age or older.
- The patient, or his or her representative, has given consent to participate in the study.
- The patient must, in the opinion of the investigator, be able to comply with all the requirements of the clinical trial.
- Patients who have previously been diagnosed with chronic pain prior to surgery.
- Patients unable to clearly understand the objectives and methodology of the study.
- Patients with chronic kidney damage with glomerular filtration < 60 ml/min (stage III-V).
- Patients with liver dysfunction with total bilirubin > 3mg/dL.
- Expected surgery lasting more than 6 hours or no extubation plan immediately after surgery.
- Patients with < 45kg and > 100kg.
- Pregnant or breastfeeding women.
- History of hypersensitivity to any of the components of lidocaine or magnesium sulfate.
- Patients who for some medical reason are contraindicated in the use of lidocaine or magnesium sulfate.
- Patients who are taking analgesics (paracetamol or non-steroidal anti-inflammatory drugs or opioids) in the 7 days prior to surgery.
- History of alcohol or drug abuse or psychiatric illness.
- History of Congestive Heart Failure or NYHA criteria III-IV or atrioventricular heart block.
- Disease of the central nervous system.
- Porphyria.
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.