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Effect of nonsteroidal anti-inflammatory drugs in the management of postoperative pain after cardiac surgery: A multicentre, randomised, placebo-controlled trial
EU CTIS ID: 2023-506299-28-00
What this study is testing
Show that the use of NSAIDs reduces pain 24 hours after cardiac surgery
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Patient aged 18 or older admitted for elective cardiac surgery under extracorporeal circulation
- Signed informed consent
You likely can't join if
- Thoracotomy approach, 2 Minimally invasive approach
- Renal replacement therapy within the last 90 days
- Depression with long-term treatment
- History of gastrointestinal ulcer
- Chronic use of NSAIDs before the operation
- Opioid dependence or chronic opioid medication
See the full eligibility criteria
- Patient aged 18 or older admitted for elective cardiac surgery under extracorporeal circulation
- Signed informed consent
- Thoracotomy approach, 2 Minimally invasive approach
- Renal replacement therapy within the last 90 days
- Depression with long-term treatment
- History of gastrointestinal ulcer
- Chronic use of NSAIDs before the operation
- Opioid dependence or chronic opioid medication
- Contraindications to the use of NSAIDs
- Emergency surgery
- Acute infectious endocarditis
- AIDS with a CD4 count <200/mm3
- Autoimmune disorder
- Advanced chronic kidney disease (CKD 4 or 5)
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.