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Metamizole as pain treatment in patients with chronic pancreatitis, a multicenter, randomized, double-blind, placebo-controlled, superiority trial
EU CTIS ID: 2023-504143-14-00
What this study is testing
To study if adding metamizole three times daily at a dosage of 1000mg to the current analgesic therapy effectively reduce pain in patients with painful chronic pancreatitis, with time since diagnosis of less than 3 years
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Confirmed chronic pancreatitis
- Abdominal pain typical for chronic pancreatitis (i.e. dull epigastric pain), NRS ≥ 3, ≥ 3 days/week for two weeks
You likely can't join if
- Endoscopic or surgical intervention < 3 months prior to inclusion
- Expected endoscopic or surgical intervention for CP within trial duration (6 weeks)
- Usage of more than 90 morphine milligram equivalents per day
- Active use of metamizole at inclusion
- Contra-indications to metamizole
- Pancreatic carcinoma
See the full eligibility criteria
- Confirmed chronic pancreatitis
- Abdominal pain typical for chronic pancreatitis (i.e. dull epigastric pain), NRS ≥ 3, ≥ 3 days/week for two weeks
- Endoscopic or surgical intervention < 3 months prior to inclusion
- Expected endoscopic or surgical intervention for CP within trial duration (6 weeks)
- Usage of more than 90 morphine milligram equivalents per day
- Active use of metamizole at inclusion
- Contra-indications to metamizole
- Pancreatic carcinoma
- • Start of amitriptyline, pregabalin or gabapentin less than 6 weeks prior to inclusion
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.