Desflurane versus Sevoflurane versus Propofol on postoperative delirium in elderly patients
EU CTIS ID: 2023-503717-30-00
What this study is testing
Our primary aim is to evaluate the effect of maintenance of general anesthesia using desflurane, sevoflurane or propofol on the incidence of postoperative delirium within the first five postoperative days in elderly patients undergoing moderate- to high-risk major noncardiac surgery.
- Phase III and phase IV (Integrated)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- 1. Provide written informed consent
- 2. ≥ 65 years of age
- 3. Scheduled for elective major noncardiac surgery with estimated time of surgery ≥ 2 hours
You likely can't join if
- 1. Patients undergoing emergency surgery
- 2. BMI > 45 kg/m2
- 3. History of diagnosed dementia
- 4. Language, vision, or hearing impairments that may compromise cognitive assessments
- 5. History of malignant hyperthermia
- 6. History of structural muscle disease
See the full eligibility criteria
- 1. Provide written informed consent
- 2. ≥ 65 years of age
- 3. Scheduled for elective major noncardiac surgery with estimated time of surgery ≥ 2 hours
- 1. Patients undergoing emergency surgery
- 2. BMI > 45 kg/m2
- 3. History of diagnosed dementia
- 4. Language, vision, or hearing impairments that may compromise cognitive assessments
- 5. History of malignant hyperthermia
- 6. History of structural muscle disease
- 7. History of organ transplantation (kidney, liver, lung, heart)
- 8. Patients undergoing hyperthermic intraperitoneal chemotherapy
- 9. ICU patients undergoing surgery
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65+ years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.