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Palliation of Dyspnea and Cough using Morphine in patients with Fibrotic Interstitial Lung Disease
EU CTIS ID: 2023-503700-81-00
What this study is testing
The main object of the study is to examine the effect of 4 weeks treatment with slow-release morphine compared to placebo on the perception of breathlessness in patients with fibrotic interstitial lung diseases.
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- fibrotic interstitial lung disease
- GAP (Gneder-Age-Physiology) score 2-3
- Presence of fibroses on HRCT (tractionbronchiectasis, honeycombing, loss of volume >10% assessed by the investigator
- MRC (Medical Research Councils) dyspnea score ≥ 3
- Informed written consent
- Age ≥ 18 år
You likely can't join if
- Regular treatment with morphine or morphine analogues
- Allergy or intolerance to morphine or morphine analogues
- Ongoing infection or exacerbation
- Patients with so severe impaired respiration that any form of worsening would be too risky (assessed by the investigator)
- Treatment with benzodiazepines (not benzodiazepine receptor agonists)
See the full eligibility criteria
- fibrotic interstitial lung disease
- GAP (Gneder-Age-Physiology) score 2-3
- Presence of fibroses on HRCT (tractionbronchiectasis, honeycombing, loss of volume >10% assessed by the investigator
- MRC (Medical Research Councils) dyspnea score ≥ 3
- Informed written consent
- Age ≥ 18 år
- Authoritative
- Regular treatment with morphine or morphine analogues
- Allergy or intolerance to morphine or morphine analogues
- Ongoing infection or exacerbation
- Patients with so severe impaired respiration that any form of worsening would be too risky (assessed by the investigator)
- Treatment with benzodiazepines (not benzodiazepine receptor agonists)
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.