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Semaglutide 2.4mg for low responders after bariatric surgery
EU CTIS ID: 2022-502164-20-01
What this study is testing
To study the weight change from 3 to 18 months after surgery (% total weight loss, TWL) in low responders after bariatric surgery who are treated with Semaglutide 2.4 mg and a lifestyle intervention and compare change in weight to patients receiving placebo and a lifestyle intervention.
- Therapeutic use (Phase IV)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Patient is ≥18 and <75 years old
- BMI before surgery was ≥ 35.0 kg/m2
- Patient is treated with group consultation at the Dutch Obesity Clinic (DOC)
- Patient has undergone a primary (banded) RYGB or (banded) sleeve gastrectomy (SG)
- Patient is in the lowest %TWL quartile, 3 months after surgery and will be enrolled in the plus module.
You likely can't join if
- Type 1 or type 2 diabetes
- Use of warfarin or other coumarin derivates
- Decreased renal function (creatinine clearance < 30 ml/min)
- Liver failure (all)
- Congestive heart failure or angina pectoris NYHA class III and IV
- Malignancy in history
See the full eligibility criteria
- Patient is ≥18 and <75 years old
- BMI before surgery was ≥ 35.0 kg/m2
- Patient is treated with group consultation at the Dutch Obesity Clinic (DOC)
- Patient has undergone a primary (banded) RYGB or (banded) sleeve gastrectomy (SG)
- Patient is in the lowest %TWL quartile, 3 months after surgery and will be enrolled in the plus module.
- Type 1 or type 2 diabetes
- Use of warfarin or other coumarin derivates
- Decreased renal function (creatinine clearance < 30 ml/min)
- Liver failure (all)
- Congestive heart failure or angina pectoris NYHA class III and IV
- Malignancy in history
- Pancreatitis (in history)
- Pregnancy / breast-feeding
- Inflammatory Bowel Disease
- Thyroid malignancy in history
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.