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Pneumococcal vaccine response in lymph nodes
EU CTIS ID: 2022-501519-15-00
What this study is testing
Determine timing of peak germinal center B cell frequency in lymph node aspirates
- Therapeutic exploratory (Phase II)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Participants between the ages of 20 and 40 years old
- Participants should be generally healthy and without substantial comorbidities, including all auto-immune diseases that are being actively treated with immunosuppressive therapy. Patients with chronic diseases that do not require immunosuppressive therapy and are stable, defined as not requiring change of therapy or hospitalization in the six weeks preceding study enrolment, might be eligible for this study.
You likely can't join if
- Subject has a BMI > 30
- Breastfeeding during the course of the study
- Documented pneumococcal vaccination and/or infection
- Documented HIV infection
- Documented primary immune disorder or primary coagulopathy
- Use of immunosuppressive medication or anticoagulants
See the full eligibility criteria
- Participants between the ages of 20 and 40 years old
- Participants should be generally healthy and without substantial comorbidities, including all auto-immune diseases that are being actively treated with immunosuppressive therapy. Patients with chronic diseases that do not require immunosuppressive therapy and are stable, defined as not requiring change of therapy or hospitalization in the six weeks preceding study enrolment, might be eligible for this study.
- Subject has a BMI > 30
- Breastfeeding during the course of the study
- Documented pneumococcal vaccination and/or infection
- Documented HIV infection
- Documented primary immune disorder or primary coagulopathy
- Use of immunosuppressive medication or anticoagulants
- Known hypersensitivity to any of the vaccine components
- Recent (i.e. <4 weeks before inclusion) surgery in axillar area or major surgery elsewhere
- Fever at time of inclusion
- Pregnancy at time of inclusion
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.