BridgeMD
A clinical trial to investigate efficacy and safety of NT 201 injections compared with placebo injections in participants aged 18 years and older with chronic neuropathic pain.
EU CTIS ID: 2022-501461-52-00
What this study is testing
To establish evidence of efficacy of NT 201 in the treatment of moderate to severe chronic PNP in patients with postherpetic neuralgia or chronic neuropathic pain after peripheral nerve injury by demonstrating superiority compared to placebo in reducing Average Daily Pain (ADP) intensity.
- Therapeutic exploratory (Phase II)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Chronic PNP that persists for at least 6 months by the time of the screening visit and is plausibly related to either an episode of herpes zoster or a peripheral nerve injury (caused by surgery or mechanical trauma).
- Documented diagnosis of either chronic neuropathic pain after peripheral nerve injury (i.e., postsurgical/post-traumatic neuropathic pain) or PHN with at least probable level of certainty according to the NeuPSIG/IASP grading system.
- A score of at least 4 out of 10 points on the Neuropathic Pain 4 Questions (DN4) questionnaire.
You likely can't join if
- Complex Regional Pain Syndrome Type 1 and Type 2.
- Any other painful condition or disease that requires regular treatment (only mild to moderate episodic migraine treated with triptans and/or non-steroidal anti-inflammatory drugs (NSAIDs), if any, is acceptable).
- Postsurgical/post-traumatic neuropathic pain due to limb amputation and/or phantom limb pain.
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65+ years, 18-64 years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.