BridgeMD
FORE-PAIN trial
EU CTIS ID: 2022-500176-63-00
What this study is testing
Determine whether intranasal (IN) fentanyl, intravenous (IV) esketamine and intranasal esketamine are non-inferior to intravenous fentanyl for analgesia in acute traumatic pain in the prehospital environment
- Therapeutic confirmatory (Phase III)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- Age ≥18 years
- Pain caused by trauma that occurred on the same day
- Administration of a strong opioid or esketamine is required for analgesia as determined by prehospital personnel
- Patient will be transported to a hospital
You likely can't join if
- Reported or estimated weight <40 or >100 kg
- Subject does not understand Dutch or English
- Subject is known to have previously declined participation in medical research
- Inability to report pain score
- Inability to give intranasal or intravenous medication
- Known severe cardiovascular disease
See the full eligibility criteria
- Age ≥18 years
- Pain caused by trauma that occurred on the same day
- Administration of a strong opioid or esketamine is required for analgesia as determined by prehospital personnel
- Patient will be transported to a hospital
- Reported or estimated weight <40 or >100 kg
- Subject does not understand Dutch or English
- Subject is known to have previously declined participation in medical research
- Inability to report pain score
- Inability to give intranasal or intravenous medication
- Known severe cardiovascular disease
- Pre-eclampsia
- Glasgow Coma Scale score < 11
The study team makes the final eligibility decision.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.